On the BI PC run regedit, then navigate to the key HKEY_LOCAL_MACHINE\SOFTWARE\Perspective Software\Blue Iris\Options, find the key hwaccel, note down the current setting, change it to 0. Then restart the BI service and see if you can then run the GUI.
I should add the setting it to 0 is a guess, I have the standard Intel Acceleration set and my value is set to 2 so you could also try that.