There's a program called "Crossover" which can run
Blue Iris on a Mac or Linux, with some shortcomings. Besides it being totally unsupported by the developer, I think BI has trouble enumerating network interfaces so you might have trouble with the web server (iOS and Android apps and UI3 web interface). It probably will also not be able to use any kind of hardware acceleration, and may not be able to play mp4 files even though it can probably create them.
You're far better off buying a cheap used small form factor windows PC. There's a post in the
wiki about choosing hardware for Blue Iris.