F22 are of little use since Iran doesn't have meaningful jets and F22 is poor at ground mission capability, with bombs strapped outside making it no better than a F16 radar signature.
But still the military planners will have to be a fool to still keep large planes like Awacs and refuelers in middle east bases, a lot of them where damage or destroyed and their production is closed. They are sitting ducks in a open air field.
Only the F35 can go inside Iranian air space but only at high altitude to try to take down mobile targets. The B1, B52 can launch standoff missiles at distance that can outrange Iranian air defense ranges, but only at static targets like buildings. B2 will not be used unless it's for MOP.
But to sustain this they will need air refuelers which have to land some where in middle east and those are easy targets. Most are parked in the open in Saudi Airbase or in Israel civilian airport. Which so far Iran hasn't targeted.
The United States has repeatedly bombed power stations in past conflicts, including World War II, the Korean War, Vietnam, the Gulf War, the Iraq War, and the Balkan Wars. The strategic objective was typically to collapse the adversary's "industrial web" and degrade command and control capabilities by disrupting the electrical grid that sustained both military forces and war-related industries.